Water‐Soluble Monofunctional Perylene and Terrylene Dyes: Powerful Labels for Single‐Enzyme Tracking

Kalina Peneva, Gueorgui Mihov, Fabian Nolde, Susana Rocha, Jun‐ichi Hotta, Kevin Braeckmans, Johan Hofkens, Hiroshi Uji‐i, Andreas Herrmann, Klaus Müllen (see publication in Journal )


All in one: Exceptionally photostable, highly fluorescent, water‐soluble, and monofunctional perylene and terrylene dyes bearing reactive groups for covalent attachment to biomolecules have been synthesized (see picture). Single‐molecule enzyme tracking revealed that single enzymes could be visualized even on a substrate with fluorescent background.